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SourcesThe studies behind what we say about acne body
Where this comes from.
6 claims · 6 studies.
C35-5
Acne = loss of C. acnes phylotype balance + dysbiosis, not hyperproliferation; antibiotics induce dysbiosis.
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C35-8
BP vehicle irritancy (surfactants/preservatives/alcohols); low-% formula without them well-tolerated.
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The record
A New, Once-daily, Optimized, Fixed Combination of Clindamycin Phosphate 1.2% and Low-concentration Benzoyl Peroxide 2.5% Gel for the Treatment of Moderate-to-Severe Acne.
C35-9
Azelaic acid — 4 mechanisms (antimicrobial, tyrosinase inhibition, free-radical scavenging, reduced neutrophil ROS).
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The record
The multiple uses of azelaic acid in dermatology: mechanism of action, preparations, and potential therapeutic applications.
C35-10
Azelaic acid also keratolytic.
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C35-11
Azelaic acid probably less effective than benzoyl peroxide on PGA (Cochrane RR 0.82).
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The record
Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha-hydroxy acid) for acne.
C35-15
Hidradenitis suppurativa >3x more prevalent in Black vs White; more severe, longer diagnostic delay.
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The record
Exploring the Experience of Black Americans Living with Hidradenitis Suppurativa in the United States Healthcare System: A Narrative Review.